c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

BACKGROUND AND AIMS: Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a tumor suppressor. Here, we investigated the role of c‐Rel in HCC. APPROACH AND...

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Detalles Bibliográficos
Autores principales: Leslie, Jack, Hunter, Jill E., Collins, Amy, Rushton, Amelia, Russell, Lauren G., Ramon‐Gil, Erik, Laszczewska, Maja, McCain, Misti, Zaki, Marco Y. W., Knox, Amber, Seow, Yixin, Sabater, Laura, Geh, Daniel, Perkins, Neil D., Reeves, Helen L., Tiniakos, Dina, Mann, Derek A., Oakley, Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Articles: Liver Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521790/
https://www.ncbi.nlm.nih.gov/pubmed/36089330
http://dx.doi.org/10.1002/hep.32781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521790/
https://www.ncbi.nlm.nih.gov/pubmed/36089330
http://dx.doi.org/10.1002/hep.32781

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