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Phosphodiesterase 10A inhibitor PF-2545920 as a prospective agent for the clinical promotion of sperm motility

Phosphodiesterase (PDE) inhibitors can improve sperm motility in patients with asthenozoospermia. However, the most commonly reported nonselective PDE inhibitor pentoxifylline and PDE5 inhibitor sildenafil have the disadvantages of requiring a high concentration and destroying sperm integrity. We ex...

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Detalles Bibliográficos
Autores principales: Yang, Yi-Ting, Yan, Bin, Li, Yu-Hua, Guo, Li-Na, Wang, Wei-Wei, Liu, Li-Jie, Yu, He-Guo, Diao, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521960/
https://www.ncbi.nlm.nih.gov/pubmed/37026191
http://dx.doi.org/10.4103/aja2022117