Investigation of evolutionary dynamics for drug resistance in 3D spheroid model system using cellular barcoding technology

Complex evolutionary dynamics governing the drug resistance is one of the major challenges in cancer treatment. Understanding these mechanisms requires a sequencing technology with higher resolution to delineate whether pre-existing or de novo drug mechanisms are behind the drug resistance. Combinin...

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Detalles Bibliográficos
Autores principales: Yalcin, Gizem Damla, Yilmaz, Kubra Celikbas, Dilber, Tugce, Acar, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521976/
https://www.ncbi.nlm.nih.gov/pubmed/37751451
http://dx.doi.org/10.1371/journal.pone.0291942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521976/
https://www.ncbi.nlm.nih.gov/pubmed/37751451
http://dx.doi.org/10.1371/journal.pone.0291942

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