Microglia-secreted TNF-α affects differentiation efficiency and viability of pluripotent stem cell-derived human dopaminergic precursors

Disease is a neurodegenerative disorder characterised by the progressive loss of dopaminergic cells of the substantia nigra pars compacta. Even though successful transplantation of dopamine-producing cells into the striatum exhibits favourable effects in animal models and clinical trials; transplant...

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Detalles Bibliográficos
Autores principales: Wenker, Shirley D., Farias, María Isabel, Gradaschi, Victoria, Garcia, Corina, Beauquis, Juan, Leal, María Celeste, Ferrari, Carina, Zeng, Xianmin, Pitossi, Fernando J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521980/
https://www.ncbi.nlm.nih.gov/pubmed/37751438
http://dx.doi.org/10.1371/journal.pone.0263021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10521980/
https://www.ncbi.nlm.nih.gov/pubmed/37751438
http://dx.doi.org/10.1371/journal.pone.0263021

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