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Production and characterization of a chimeric antigen, based on nucleocapsid of SARS-CoV-2 fused to the extracellular domain of human CD154 in HEK-293 cells as a vaccine candidate against COVID-19

Despite that more than one hundred vaccines against SARS-CoV-2 have been developed and that some of them were evaluated in clinical trials, the latest results revealed that these vaccines still face great challenges. Among the components of the virus, the N-protein constitutes an attractive target f...

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Detalles Bibliográficos
Autores principales: Lao, Thailin, Avalos, Ileanet, Rodríguez, Elsa María, Zamora, Yasser, Rodriguez, Alianet, Ramón, Ailyn, Alvarez, Yanitza, Cabrales, Ania, Andújar, Ivan, González, Luis Javier, Puente, Pedro, García, Cristina, Gómez, Leonardo, Valdés, Rodolfo, Estrada, Mario Pablo, Carpio, Yamila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522030/
https://www.ncbi.nlm.nih.gov/pubmed/37751460
http://dx.doi.org/10.1371/journal.pone.0288006