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11β-hydroxysteroid dehydrogenase type-II activity is affected by grapefruit juice and intense muscular work

OBJECTIVE: The enzymatic activity of 11β-hydroxysteroid dehydrogenase-2 (11β-HSD2) is key to protecting mineral corticoid receptors from cortisol and has been implicated in blood pressure regulation. Grapefruit juice (GFJ) and acidity are thought to inhibit this enzyme in vitro. This study examines...

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Detalles Bibliográficos
Autores principales: Kargl, Christopher, Arshad, Mohammad, Salman, Fahad, Schurman, Regina C., Del Corral, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Endocrinologia e Metabologia 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522063/
https://www.ncbi.nlm.nih.gov/pubmed/28977167
http://dx.doi.org/10.1590/2359-3997000000296