Sunitinib in the therapy of malignant paragangliomas: report on the efficacy in a SDHB mutation carrier and review of the literature

Metastatic pheochromocytomas (PHEOs) and paragangliomas (sPGLs) are rare neural crest-derived tumors with a poor prognosis. About 50% of them are due to germ-line mutations of the SDHB gene. At present, there is no cure for these tumors. Their therapy is palliative and represented by different optio...

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Detalles Bibliográficos
Autores principales: Canu, Letizia, Pradella, Silvia, Rapizzi, Elena, Fucci, Rossella, Valeri, Andrea, Briganti, Vittorio, Giachè, Valentino, Parenti, Gabriele, Ercolino, Tonino, Mannelli, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Endocrinologia e Metabologia 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522113/
https://www.ncbi.nlm.nih.gov/pubmed/27737332
http://dx.doi.org/10.1590/2359-3997000000217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522113/
https://www.ncbi.nlm.nih.gov/pubmed/27737332
http://dx.doi.org/10.1590/2359-3997000000217

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