Triiodothyronine (T(3)) upregulates the expression of proto-oncogene TGFA independent of MAPK/ERK pathway activation in the human breast adenocarcinoma cell line, MCF7

OBJECTIVE: To verify the physiological action of triiodothyronine T(3) on the expression of transforming growth factor α (TGFA) mRNA in MCF7 cells by inhibition of RNA Polymerase II and the MAPK/ERK pathway MATERIALS AND METHODS: The cell line was treated with T(3) at a physiological dose (10(−9)M)...

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Detalles Bibliográficos
Autores principales: Silva, Tabata M., Moretto, Fernanda C. F., Sibio, Maria T. De, Gonçalves, Bianca M., Oliveira, Miriane, Olimpio, Regiane M. C., Oliveira, Diego A. M., Costa, Sarah M. B., Deprá, Igor C., Namba, Vickeline, Nunes, Maria T., Nogueira, Célia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Endocrinologia e Metabologia 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522138/
https://www.ncbi.nlm.nih.gov/pubmed/30916164
http://dx.doi.org/10.20945/2359-3997000000114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522138/
https://www.ncbi.nlm.nih.gov/pubmed/30916164
http://dx.doi.org/10.20945/2359-3997000000114

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