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Use of whole genome sequencing to identify low‐frequency mutations in SARS‐CoV‐2 patients treated with remdesivir

BACKGROUND: Remdesivir (RDV) has been shown to reduce hospitalization and mortality in COVID‐19 patients. Resistance mutations caused by RDV are rare and have been predominantly reported in patients who are on prolonged therapy and immunocompromised. We investigate the effects of RDV treatment on in...

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Detalles Bibliográficos
Autores principales: Nirmalarajah, Kuganya, Yim, Winfield, Aftanas, Patryk, Li, Angel X., Shigayeva, Altynay, Yip, Lily, Zhong, Zoe, McGeer, Allison J., Maguire, Finlay, Mubareka, Samira, Kozak, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522481/
https://www.ncbi.nlm.nih.gov/pubmed/37752062
http://dx.doi.org/10.1111/irv.13179