MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange

Presentation of antigenic peptides by major histocompatibility complex class II (MHC-II) proteins determines T helper cell reactivity. The MHC-II genetic locus displays a large degree of allelic polymorphism influencing the peptide repertoire presented by the resulting MHC-II protein allotypes. Duri...

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Detalles Bibliográficos
Autores principales: Abualrous, Esam T., Stolzenberg, Sebastian, Sticht, Jana, Wieczorek, Marek, Roske, Yvette, Günther, Matthias, Dähn, Steffen, Boesen, Benedikt B., Calvo, Marcos Martínez, Biese, Charlotte, Kuppler, Frank, Medina-García, Álvaro, Álvaro-Benito, Miguel, Höfer, Thomas, Noé, Frank, Freund, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522485/
https://www.ncbi.nlm.nih.gov/pubmed/37142807
http://dx.doi.org/10.1038/s41589-023-01316-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522485/
https://www.ncbi.nlm.nih.gov/pubmed/37142807
http://dx.doi.org/10.1038/s41589-023-01316-3

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