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Correlation of mucosal healing endpoints with long-term clinical and patient-reported outcomes in ulcerative colitis

BACKGROUND: We evaluated the clinical relevance of achieving histologic endoscopic mucosal improvement (HEMI) and the more stringent target of histologic endoscopic mucosal remission (HEMR) in the phase 3 maintenance trial of upadacitinib for moderately to severely active ulcerative colitis. METHODS...

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Detalles Bibliográficos
Autores principales: Parkes, Gareth, Ungaro, Ryan C., Danese, Silvio, Abreu, Maria T., Arenson, Ethan, Zhou, Wen, Ilo, Dapo, Laroux, F. Stephen, Deng, Huiwen, Sanchez Gonzalez, Yuri, Peyrin-Biroulet, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522527/
https://www.ncbi.nlm.nih.gov/pubmed/37490069
http://dx.doi.org/10.1007/s00535-023-02013-7