Dehydroascorbic acid sensitizes cancer cells to system x(c)(-) inhibition-induced ferroptosis by promoting lipid droplet peroxidation

Since the discovery of ferroptosis, it has been postulated that this type of cell death could be utilized in treatments for cancer. Unfortunately, several highly aggressive tumor models are resistant to the pharmacological induction of ferroptosis. However, with the use of combined therapies, it is...

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Detalles Bibliográficos
Autores principales: Ferrada, Luciano, Barahona, María José, Vera, Matías, Stockwell, Brent R., Nualart, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522586/
https://www.ncbi.nlm.nih.gov/pubmed/37752118
http://dx.doi.org/10.1038/s41419-023-06153-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522586/
https://www.ncbi.nlm.nih.gov/pubmed/37752118
http://dx.doi.org/10.1038/s41419-023-06153-9

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