Ictogenesis proceeds through discrete phases in hippocampal CA1 seizures in mice

Epilepsy is characterized by spontaneous non-provoked seizures, yet the mechanisms that trigger a seizure and allow its evolution remain underexplored. To dissect out phases of ictogenesis, we evoked hypersynchronous activity with optogenetic stimulation. Focal optogenetic activation of putative exc...

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Detalles Bibliográficos
Autores principales: Mueller, John-Sebastian, Tescarollo, Fabio C., Huynh, Trong, Brenner, Daniel A., Valdivia, Daniel J., Olagbegi, Kanyin, Sangappa, Sahana, Chen, Spencer C., Sun, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522592/
https://www.ncbi.nlm.nih.gov/pubmed/37752179
http://dx.doi.org/10.1038/s41467-023-41711-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522592/
https://www.ncbi.nlm.nih.gov/pubmed/37752179
http://dx.doi.org/10.1038/s41467-023-41711-x

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