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Pressure overload-induced systolic heart failure is associated with characteristic myocardial microRNA expression signature and post-transcriptional gene regulation in male rats

Although systolic function characteristically shows gradual impairment in pressure overload (PO)-evoked left ventricular (LV) hypertrophy (LVH), rapid progression to congestive heart failure (HF) occurs in distinct cases. The molecular mechanisms for the differences in maladaptation are unknown. Her...

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Detalles Bibliográficos
Autores principales: Ruppert, Mihály, Korkmaz-Icöz, Sevil, Benczik, Bettina, Ágg, Bence, Nagy, Dávid, Bálint, Tímea, Sayour, Alex Ali, Oláh, Attila, Barta, Bálint András, Benke, Kálmán, Ferdinandy, Péter, Karck, Matthias, Merkely, Béla, Radovits, Tamás, Szabó, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522609/
https://www.ncbi.nlm.nih.gov/pubmed/37752166
http://dx.doi.org/10.1038/s41598-023-43171-1