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Recovery of the histamine H(3) receptor activity lost in yeast cells through error-prone PCR and in vivo selection
G protein-coupled receptors (GPCRs) are the largest protein family in humans and are important drug targets. Yeast, especially Saccharomyces cerevisiae, is a useful host for modifying the function and stability of GPCRs through protein engineering, which is advantageous for mammalian cells. When GPC...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522717/ https://www.ncbi.nlm.nih.gov/pubmed/37752220 http://dx.doi.org/10.1038/s41598-023-43389-z |