Cargando…

Recovery of the histamine H(3) receptor activity lost in yeast cells through error-prone PCR and in vivo selection

G protein-coupled receptors (GPCRs) are the largest protein family in humans and are important drug targets. Yeast, especially Saccharomyces cerevisiae, is a useful host for modifying the function and stability of GPCRs through protein engineering, which is advantageous for mammalian cells. When GPC...

Descripción completa

Detalles Bibliográficos
Autores principales: Watanabe, Ayami, Nakajima, Ami, Shiroishi, Mitsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522717/
https://www.ncbi.nlm.nih.gov/pubmed/37752220
http://dx.doi.org/10.1038/s41598-023-43389-z

Ejemplares similares