Dipyridamole activates adenosine A2B receptor and AMPK/cAMP signaling and promotes myogenic differentiation of myoblastic C2C12 cells

Introduction: Sarcopenia is defined as a loss of muscle mass and strength. ATP homeostasis is crucial during myogenesis. We determined how the purinergic system modulates myogenesis using dipyridamole (blocks adenosine taken up by the cells) and tenofovir (inhibits ATP release) in a myoblast cell li...

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Detalles Bibliográficos
Autores principales: Marco-Bonilla, Miguel, Herencia, Raquel, Fresnadillo, María, Huete-Toral, Fernando, Carracedo, Gonzalo, Largo, Raquel, Herrero-Beaumont, Gabriel, Mediero, Aránzazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522837/
https://www.ncbi.nlm.nih.gov/pubmed/37771723
http://dx.doi.org/10.3389/fphar.2023.1247664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522837/
https://www.ncbi.nlm.nih.gov/pubmed/37771723
http://dx.doi.org/10.3389/fphar.2023.1247664

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