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Hyperpolarized [1-(13)C]pyruvate Magnetic Resonance Spectroscopy Shows That Agmatine Increased Lactate Production in the Brain of Type 2 Diabetic Mice

PURPOSE: Type 2 diabetes mellitus (T2DM) is associated with a 2-fold increased risk of developing Alzheimer’s disease. In earlier research, agmatine has been demonstrated to alleviate diabetes symptoms and increase cognitive performance. However, it is unclear whether the improvement of cognitive fu...

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Detalles Bibliográficos
Autores principales: Choi, Young-Suk, Song, Jae Eun, Kim, Eosu, Kim, Chul Hoon, Lee, Jong Eun, Song, Ho-Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522877/
https://www.ncbi.nlm.nih.gov/pubmed/37727922
http://dx.doi.org/10.3349/ymj.2022.0554