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ZEB2 and MEIS1 independently contribute to hematopoiesis via early hematopoietic enhancer activation

Cell differentiation is achieved by acquiring a cell type-specific transcriptional program and epigenetic landscape. While the cell type-specific patterning of enhancers has been shown to precede cell fate decisions, it remains unclear how regulators of these enhancers are induced to initiate cell s...

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Detalles Bibliográficos
Autores principales: Kitagawa, Yohko, Ikenaka, Akihiro, Sugimura, Ryohichi, Niwa, Akira, Saito, Megumu K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522983/
https://www.ncbi.nlm.nih.gov/pubmed/37771659
http://dx.doi.org/10.1016/j.isci.2023.107893