Nimbolide-based nanomedicine inhibits breast cancer stem-like cells by epigenetic reprogramming of DNMTs-SFRP1-Wnt/β-catenin signaling axis

Triple-negative breast cancer (TNBC) harbors a high percentage of breast cancer stem-like cells (BCSCs) that significantly contribute to poor prognosis, metastasis, and relapse of the disease. Thus, targeting BCSCs could be a promising approach to combat TNBC. In this context, we investigated nimbol...

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Detalles Bibliográficos
Autores principales: Mohapatra, Priyanka, Madhulika, Swati, Behera, Somalisa, Singh, Priya, Sa, Pratikshya, Prasad, Punit, Swain, Rajeeb Kumar, Sahoo, Sanjeeb Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523002/
https://www.ncbi.nlm.nih.gov/pubmed/37771911
http://dx.doi.org/10.1016/j.omtn.2023.102031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523002/
https://www.ncbi.nlm.nih.gov/pubmed/37771911
http://dx.doi.org/10.1016/j.omtn.2023.102031

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