Cargando…
Nimbolide-based nanomedicine inhibits breast cancer stem-like cells by epigenetic reprogramming of DNMTs-SFRP1-Wnt/β-catenin signaling axis
Triple-negative breast cancer (TNBC) harbors a high percentage of breast cancer stem-like cells (BCSCs) that significantly contribute to poor prognosis, metastasis, and relapse of the disease. Thus, targeting BCSCs could be a promising approach to combat TNBC. In this context, we investigated nimbol...
Autores principales: | Mohapatra, Priyanka, Madhulika, Swati, Behera, Somalisa, Singh, Priya, Sa, Pratikshya, Prasad, Punit, Swain, Rajeeb Kumar, Sahoo, Sanjeeb Kumar |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523002/ https://www.ncbi.nlm.nih.gov/pubmed/37771911 http://dx.doi.org/10.1016/j.omtn.2023.102031 |
Ejemplares similares
-
Insights from nanotechnology in COVID-19: prevention, detection, therapy and immunomodulation
por: Singh, Priya, et al.
Publicado: (2021) -
Nimbolide targeting SIRT1 mitigates intervertebral disc degeneration by reprogramming cholesterol metabolism and inhibiting inflammatory signaling
por: Teng, Yun, et al.
Publicado: (2023) -
Review on Molecular and Chemopreventive Potential of Nimbolide in Cancer
por: Elumalai, Perumal, et al.
Publicado: (2014) -
DNMTs are required for delayed genome instability caused by radiation
por: Armstrong, Christine A., et al.
Publicado: (2012) -
Nimbolide Inhibits SOD2 to Control Pancreatic Ductal Adenocarcinoma Growth and Metastasis
por: Mehmetoglu-Gurbuz, Tugba, et al.
Publicado: (2023)