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The gasdermins: a pore-forming protein family expressed in the epidermis

Gasdermins comprise a family of pore-forming proteins, which play critical roles in (auto)inflammatory diseases and cancer. They are expressed as self-inhibited precursor proteins consisting of an aminoterminal cytotoxic effector domain (NT-GSDM) and a carboxyterminal inhibitor domain (GSDM-CT) sepa...

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Detalles Bibliográficos
Autores principales: Slaufova, Marta, Karakaya, Tugay, Di Filippo, Michela, Hennig, Paulina, Beer, Hans-Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523161/
https://www.ncbi.nlm.nih.gov/pubmed/37771587
http://dx.doi.org/10.3389/fimmu.2023.1254150