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The central nervous system is a potential reservoir and possible origin of drug resistance in hepatitis B infection

BACKGROUND: The significance of hepatitis B virus (HBV) in cerebrospinal fluid (CSF) is unclear. METHODS: Synchronous serum and CSF samples were collected from 13 patients. HBV DNA, full-length genome, quasispecies, phylogenetic tree, compartmentalization and mutation of the reverse transcriptase (R...

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Detalles Bibliográficos
Autores principales: Xu, Lijun, Zhou, Minghan, Peng, Xiuming, Xu, Yufan, Huang, Fan, Wang, Linyun, Peng, Xiaorong, Yang, Zongxing, Tao, Ran, Lang, Guanjing, Cao, Qing, Li, Minwei, Huang, Ying, Zhu, Biao, Xu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523273/
https://www.ncbi.nlm.nih.gov/pubmed/37771603
http://dx.doi.org/10.1016/j.jve.2023.100348