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The central nervous system is a potential reservoir and possible origin of drug resistance in hepatitis B infection
BACKGROUND: The significance of hepatitis B virus (HBV) in cerebrospinal fluid (CSF) is unclear. METHODS: Synchronous serum and CSF samples were collected from 13 patients. HBV DNA, full-length genome, quasispecies, phylogenetic tree, compartmentalization and mutation of the reverse transcriptase (R...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523273/ https://www.ncbi.nlm.nih.gov/pubmed/37771603 http://dx.doi.org/10.1016/j.jve.2023.100348 |