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Altered intestinal barrier contributes to cognitive impairment in old mice with constipation after sevoflurane anesthesia
BACKGROUND: Elderly patients have a high risk of developing postoperative cognitive dysfunction (POCD). Gastrointestinal disorders, such as constipation, in the elderly population may be involved in the pathogenesis of neurological disorders by promoting inflammatory responses due to a ‘leaky gut’....
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523324/ https://www.ncbi.nlm.nih.gov/pubmed/37771755 http://dx.doi.org/10.3389/fnut.2023.1117028 |