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Altered intestinal barrier contributes to cognitive impairment in old mice with constipation after sevoflurane anesthesia

BACKGROUND: Elderly patients have a high risk of developing postoperative cognitive dysfunction (POCD). Gastrointestinal disorders, such as constipation, in the elderly population may be involved in the pathogenesis of neurological disorders by promoting inflammatory responses due to a ‘leaky gut’....

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Detalles Bibliográficos
Autores principales: Zhao, Tianyun, Lu, Junming, Qin, Jingwen, Chen, Yanxin, Shi, Ziwen, Wei, Wei, Xiong, Peng, Ma, Daqing, Song, Xingrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523324/
https://www.ncbi.nlm.nih.gov/pubmed/37771755
http://dx.doi.org/10.3389/fnut.2023.1117028