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Deconstructing Protein Binding of Sulfonamides and Sulfonamide Analogues

[Image: see text] Sulfonamides are one of the most important pharmacophores in medicinal chemistry, and sulfonamide analogues have gained substantial interest in recent years. However, the protein interactions of sulfonamides and especially of their analogues are underexplored. Using FKBP12 as a mod...

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Detalles Bibliográficos
Autores principales: Purder, Patrick L., Meyners, Christian, Sugiarto, Wisely Oki, Kolos, Jürgen, Löhr, Frank, Gebel, Jakob, Nehls, Thomas, Dötsch, Volker, Lermyte, Frederik, Hausch, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523370/
https://www.ncbi.nlm.nih.gov/pubmed/37772190
http://dx.doi.org/10.1021/jacsau.3c00241