Cargando…

Engineered bone marrow as a clinically relevant ex vivo model for primary bone cancer research and drug screening

Osteosarcoma (OS) is the most common primary malignant bone cancer in children and adolescents. While numerous other cancers now have promising therapeutic advances, treatment options for OS have remained unchanged since the advent of standard chemotherapeutics and offer less than a 25% 5-y survival...

Descripción completa

Detalles Bibliográficos
Autores principales: Griffin, Katherine H., Thorpe, Steven W., Sebastian, Aimy, Hum, Nicholas R., Coonan, Thomas P., Sagheb, Isabel S., Loots, Gabriela G., Randall, R. Lor, Leach, J. Kent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523456/
https://www.ncbi.nlm.nih.gov/pubmed/37729195
http://dx.doi.org/10.1073/pnas.2302101120