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Engineered bone marrow as a clinically relevant ex vivo model for primary bone cancer research and drug screening
Osteosarcoma (OS) is the most common primary malignant bone cancer in children and adolescents. While numerous other cancers now have promising therapeutic advances, treatment options for OS have remained unchanged since the advent of standard chemotherapeutics and offer less than a 25% 5-y survival...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523456/ https://www.ncbi.nlm.nih.gov/pubmed/37729195 http://dx.doi.org/10.1073/pnas.2302101120 |