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An intraflagellar transport dependent negative feedback regulates the MAPKKK DLK-1 to protect cilia from degeneration

Primary cilia are specialized organelles supporting the development and function of cells and organisms. Intraflagellar transport (IFT) is essential for cilia formation, maintenance, and function. In C. elegans ciliated sensory neurons, IFT interacts with signaling molecules to generate distinct mor...

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Detalles Bibliográficos
Autores principales: Sun, Yue, Jin, Yishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523469/
https://www.ncbi.nlm.nih.gov/pubmed/37722038
http://dx.doi.org/10.1073/pnas.2302801120