BRWD3 promotes KDM5 degradation to maintain H3K4 methylation levels

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Histone modifications are critical for regulating chromatin structure and gene expression. Dysregulation of histone modifications likely contributes to disease states and cancer. Depletion of the chromatin-binding protein BRWD3 (Bromodomain and WD repeat-containing protein 3), a known substrate-spec...

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Detalles Bibliográficos
Autores principales: Han, Dongsheng, Schaffner, Samantha H., Davies, Jonathan P., Benton, Mary Lauren, Plate, Lars, Nordman, Jared T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523488/
https://www.ncbi.nlm.nih.gov/pubmed/37722046
http://dx.doi.org/10.1073/pnas.2305092120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523488/
https://www.ncbi.nlm.nih.gov/pubmed/37722046
http://dx.doi.org/10.1073/pnas.2305092120

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