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Real-time monitoring strategies for optimization of in vitro transcription and quality control of RNA

RNA-based therapeutics and vaccines are opening up new avenues for modern medicine. To produce these useful RNA-based reagents, in vitro transcription (IVT) is an important reaction that primarily determines the yield and quality of the product. Therefore, IVT condition should be well optimized to a...

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Detalles Bibliográficos
Autores principales: Lee, Kyung Hyun, Song, Jaehwi, Kim, Seongcheol, Han, Seung Ryul, Lee, Seong-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523567/
https://www.ncbi.nlm.nih.gov/pubmed/37771458
http://dx.doi.org/10.3389/fmolb.2023.1229246