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Assessment of Drug-Induced Liver Injury through Cell Morphology and Gene Expression Analysis

[Image: see text] Drug-induced liver injury (DILI) is a significant concern in drug development, often leading to drug withdrawal. Although many studies aim to identify biomarkers and gene/pathway signatures related to liver toxicity and aim to predict DILI compounds, this remains a challenge in dru...

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Detalles Bibliográficos
Autores principales: Lejal, Vanille, Cerisier, Natacha, Rouquié, David, Taboureau, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523580/
https://www.ncbi.nlm.nih.gov/pubmed/37652439
http://dx.doi.org/10.1021/acs.chemrestox.2c00381