Refine and Strengthen SAR-Based Read-Across by Considering Bioactivation and Modes of Action

[Image: see text] Structure–activity relationship (SAR)-based read-across is an important and effective method to establish the safety of a data-poor target chemical (structure of interest (SOI)) using hazard data from structurally similar source chemicals (analogues). Many methods use quantitative...

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Detalles Bibliográficos
Autores principales: Yan, Gang, Rose, Jane, Ellison, Corie, Mudd, Ashley M., Zhang, Xiaoling, Wu, Shengde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523590/
https://www.ncbi.nlm.nih.gov/pubmed/37594911
http://dx.doi.org/10.1021/acs.chemrestox.3c00156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523590/
https://www.ncbi.nlm.nih.gov/pubmed/37594911
http://dx.doi.org/10.1021/acs.chemrestox.3c00156

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