Cargando…

Refine and Strengthen SAR-Based Read-Across by Considering Bioactivation and Modes of Action

[Image: see text] Structure–activity relationship (SAR)-based read-across is an important and effective method to establish the safety of a data-poor target chemical (structure of interest (SOI)) using hazard data from structurally similar source chemicals (analogues). Many methods use quantitative...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Gang, Rose, Jane, Ellison, Corie, Mudd, Ashley M., Zhang, Xiaoling, Wu, Shengde
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523590/ https://www.ncbi.nlm.nih.gov/pubmed/37594911 http://dx.doi.org/10.1021/acs.chemrestox.3c00156

Ejemplares similares

Identifying chemicals based on receptor binding/bioactivation/mechanistic explanation associated with potential to elicit hepatotoxicity and to support structure activity relationship-based read-across
por: Wu, Shengde, et al.
Publicado: (2023)

t(4) report(): Supporting Read-Across Using Biological Data
por: Zhu, Hao, et al.
Publicado: (2016)

Exploring the Mode of Action of Bioactive Compounds by Microfluidic Transcriptional Profiling in Mycobacteria
por: Murima, Paul, et al.
Publicado: (2013)

Evaluation of Flexural Behavior of Textile-Reinforced Mortar-Strengthened RC Beam Considering Strengthening Limit
por: Park, Jongho, et al.
Publicado: (2021)

Health Synergies across International Sustainability and Development Agendas: Pathways to Strengthen National Action
por: Bowen, Kathryn J., et al.
Publicado: (2021)

A Review on Plant Bioactive Compounds and Their Modes of Action Against Coronavirus Infection
por: Remali, Juwairiah, et al.
Publicado: (2021)

Comparison between endocrine activity assessed using ToxCast/Tox21 database and human plasma concentration of sunscreen active ingredients/UV filters
por: Onyango, David O, et al.
Publicado: (2023)

Bioactivities and Mode of Actions of Dibutyl Phthalates and Nocardamine from Streptomyces sp. H11809
por: Mahmud, Fauze, et al.
Publicado: (2022)

Features to Consider When Selecting Displays for Remote Reading
por: Silosky, Michael, et al.
Publicado: (2022)

Chemical Safety Assessment Using Read-Across: Assessing the Use of Novel Testing Methods to Strengthen the Evidence Base for Decision Making
por: Berggren, Elisabet, et al.
Publicado: (2015)

Dynamic mode decomposition in adaptive mesh refinement and coarsening simulations
por: Barros, Gabriel F., et al.
Publicado: (2021)

Reliability Analysis of CFRP-Strengthened RC Bridges Considering Size Effect of CFRP
por: Xie, Hui-Bing, et al.
Publicado: (2019)

Phenotype Refinement Strengthens the Association of AHR and CYP1A1 Genotype with Caffeine Consumption
por: McMahon, George, et al.
Publicado: (2014)

Failure-modes-based software reading
por: Zhu, Yang-Ming
Publicado: (2017)

t(4) report: Toward Good Read-Across Practice (GRAP) Guidance
por: Ball, Nicholas, et al.
Publicado: (2016)

Reading therapy strengthens top–down connectivity in patients with pure alexia
por: Woodhead, Zoe V. J., et al.
Publicado: (2013)

From action systems to distributed systems: the refinement approach
por: Petre, Luigia, et al.
Publicado: (2016)

Planning action for strengthening the ecosystem for Ayurvedic research
por: Katoch, V.M.
Publicado: (2018)

Consolidated criteria for strengthening reporting of health research involving indigenous peoples: the CONSIDER statement
por: Huria, Tania, et al.
Publicado: (2019)

Library science and the information society: Aspects to consider with regard to reading practices
por: RAMÍREZ LEYVA, ELSA MARGARITA
Publicado: (1999)

Considering science needs to deliver actionable science
por: Bisbal, Gustavo A., et al.
Publicado: (2022)

Elucidating the modes of action for bioactive compounds in a cell-specific manner by large-scale chemically-induced transcriptomics
por: Iwata, Michio, et al.
Publicado: (2017)

Cynara cardunculus Crude Extract as a Powerful Natural Herbicide and Insight into the Mode of Action of Its Bioactive Molecules
por: Ben Kaab, Sofiene, et al.
Publicado: (2020)

Strengthening of a Near β-Ti Alloy through β Grain Refinement and Stress-Induced α Precipitation
por: Chen, Wei, et al.
Publicado: (2020)

CALL FOR ACTION: STRENGTHENING LONG-TERM CARE IN NEPAL
por: Dhakal, Usha, et al.
Publicado: (2022)

Antimicrobial resistance: Strengthening surveillance for public health action
por: Bertagnolio, Silvia, et al.
Publicado: (2023)

On the Mode of Action of Strychnia
Publicado: (1868)

On the Mode of Action of Strychnia
por: Spence, Alexander Ingram
Publicado: (1866)

Bioactive Molecules and Their Mechanisms of Action
por: Wang, Dongdong, et al.
Publicado: (2019)

Comparison of Short-Read Sequence Aligners Indicates Strengths and Weaknesses for Biologists to Consider
por: Musich, Ryan, et al.
Publicado: (2021)

Quantifying Analogue Suitability for SAR-Based Read-Across Toxicological Assessment
por: Lester, Cathy, et al.
Publicado: (2023)

Accurate reconstruction of viral genomes in human cells from short reads using iterative refinement
por: Lee, Sau-Dan, et al.
Publicado: (2022)

Editorial: Reading, literature, and psychology in action
por: Davis, Philip, et al.
Publicado: (2023)

Practical application of the interim internal threshold of toxicological concern (iTTC): a case study based on clinical data
por: Najjar, Abdulkarim, et al.
Publicado: (2022)

Correction to: Practical application of the interim internal threshold of toxicological concern (iTTC): a case study based on clinical data
por: Najjar, Abdulkarim, et al.
Publicado: (2022)

Comparative Omics-Driven Genome Annotation Refinement: Application across Yersiniae
por: Schrimpe-Rutledge, Alexandra C., et al.
Publicado: (2012)

The Role of Inhibitory Interneurons in Circuit Assembly and Refinement Across Sensory Cortices
por: Ferrer, Camilo, et al.
Publicado: (2022)

Updating and refining estimates of typhoid fever burden for public health action
por: Crump, John A
Publicado: (2014)

Genomic Relatedness Strengthens Genetic Connectedness Across Management Units
por: Yu, Haipeng, et al.
Publicado: (2017)

Dealing with structural variability in molecular replacement and crystallographic refinement through normal-mode analysis
por: Delarue, Marc
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_7ekefm4n07fr0hsnjlfnbvkcrm