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A PAX6-regulated receptor tyrosine kinase pairs with a pseudokinase to activate immune defense upon oomycete recognition in Caenorhabditis elegans

Oomycetes were recently discovered as natural pathogens of Caenorhabditis elegans, and pathogen recognition alone was shown to be sufficient to activate a protective transcriptional program characterized by the expression of multiple chitinase-like (chil) genes. However, the molecular mechanisms und...

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Detalles Bibliográficos
Autores principales: Drury, Florence, Grover, Manish, Hintze, Mark, Saunders, Jonathan, Fasseas, Michael K., Constantinou, Charis, Barkoulas, Michalis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523662/
https://www.ncbi.nlm.nih.gov/pubmed/37725647
http://dx.doi.org/10.1073/pnas.2300587120