Cargando…

A PAX6-regulated receptor tyrosine kinase pairs with a pseudokinase to activate immune defense upon oomycete recognition in Caenorhabditis elegans

Oomycetes were recently discovered as natural pathogens of Caenorhabditis elegans, and pathogen recognition alone was shown to be sufficient to activate a protective transcriptional program characterized by the expression of multiple chitinase-like (chil) genes. However, the molecular mechanisms und...

Descripción completa

Detalles Bibliográficos
Autores principales:	Drury, Florence, Grover, Manish, Hintze, Mark, Saunders, Jonathan, Fasseas, Michael K., Constantinou, Charis, Barkoulas, Michalis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523662/ https://www.ncbi.nlm.nih.gov/pubmed/37725647 http://dx.doi.org/10.1073/pnas.2300587120

Ejemplares similares

Chemosensory Neurons Modulate the Response to Oomycete Recognition in Caenorhabditis elegans
por: Fasseas, Michael K., et al.
Publicado: (2021)

C. elegans as a new tractable host to study infections by animal pathogenic oomycetes
por: Grover, Manish, et al.
Publicado: (2021)

Infection of C. elegans by Haptoglossa Species Reveals Shared Features in the Host Response to Oomycete Detection
por: Grover, Manish, et al.
Publicado: (2021)

A role for the fusogen eff-1 in epidermal stem cell number robustness in Caenorhabditis elegans
por: Koneru, Sneha L., et al.
Publicado: (2021)

A Cell Fate Switch in the Caenorhabditis elegans Seam Cell Lineage Occurs Through Modulation of the Wnt Asymmetry Pathway in Response to Temperature Increase
por: Hintze, Mark, et al.
Publicado: (2020)

Phenotypic Robustness of Epidermal Stem Cell Number in C. elegans Is Modulated by the Activity of the Conserved N-acetyltransferase nath-10/NAT10
por: Hintze, Mark, et al.
Publicado: (2021)

Cryptic genetic variation in a heat shock protein modifies the outcome of a mutation affecting epidermal stem cell development in C. elegans
por: Koneru, Sneha L., et al.
Publicado: (2021)

Targeted DamID in C. elegans reveals a direct role for LIN-22 and NHR-25 in antagonizing the epidermal stem cell fate
por: Katsanos, Dimitris, et al.
Publicado: (2022)

A pals-25 gain-of-function allele triggers systemic resistance against natural pathogens of C. elegans
por: Gang, Spencer S., et al.
Publicado: (2022)

Mitochondria-mediated defense mechanisms against pathogens in Caenorhabditis elegans
por: Kwon, Sujeong, et al.
Publicado: (2018)

Plants versus Fungi and Oomycetes: Pathogenesis, Defense and Counter-Defense in the Proteomics Era
por: El Hadrami, Abdelbasset, et al.
Publicado: (2012)

Evolution of New cis-Regulatory Motifs Required for Cell-Specific Gene Expression in Caenorhabditis
por: Barkoulas, Michalis, et al.
Publicado: (2016)

What is the point of pseudokinases?
por: Raju, Saravanan, et al.
Publicado: (2015)

Staphylococcal Biofilm Exopolysaccharide Protects against Caenorhabditis elegans Immune Defenses
por: Begun, Jakob, et al.
Publicado: (2007)

Candida albicans Infection of Caenorhabditis elegans Induces Antifungal Immune Defenses
por: Pukkila-Worley, Read, et al.
Publicado: (2011)

piRNAs and siRNAs collaborate in Caenorhabditis elegans genome defense
por: Billi, Allison C, et al.
Publicado: (2012)

Surveillance Immunity: An Emerging Paradigm of Innate Defense Activation in Caenorhabditis elegans
por: Pukkila-Worley, Read
Publicado: (2016)

Pseudokinase is active after all
por: LeBrasseur, Nicole
Publicado: (2008)

Nucleotide-binding mechanisms in pseudokinases
por: Hammarén, Henrik M., et al.
Publicado: (2016)

Tribbles Pseudokinases in Colorectal Cancer
por: Ferreira, Bibiana I., et al.
Publicado: (2021)

Pseudokinases, Tribbles Proteins and Cancer
por: Velasco, Guillermo, et al.
Publicado: (2023)

Gene expression profiling of epidermal cell types in C. elegans using Targeted-DamID
por: Katsanos, Dimitris, et al.
Publicado: (2021)

Have It Your Way: How Polymorphic, Injected Kinases and Pseudokinases Enable Toxoplasma to Subvert Host Defenses
por: Boothroyd, John C.
Publicado: (2013)

Caenorhabditis Elegans
Publicado: (2000)

Diverse Functions of mRNA Metabolism Factors in Stress Defense and Aging of Caenorhabditis elegans
por: Rousakis, Aris, et al.
Publicado: (2014)

The fatty acid oleate is required for innate immune activation and pathogen defense in Caenorhabditis elegans
por: Anderson, Sarah M., et al.
Publicado: (2019)

Evolution of Caenorhabditis elegans host defense under selection by the bacterial parasite Serratia marcescens
por: Penley, McKenna J., et al.
Publicado: (2017)

Caenorhabditis elegans processes sensory information to choose between freeloading and self-defense strategies
por: Schiffer, Jodie A, et al.
Publicado: (2020)

SCYL pseudokinases in neuronal function and survival
por: Pelletier, Stephane
Publicado: (2016)

Pharmacological Targeting of the Pseudokinase Her3
por: Xie, Ting, et al.
Publicado: (2014)

Rapid defense mechanism suppression during viral- oomycete disease complex formation
por: Philosoph, Amit M., et al.
Publicado: (2023)

The Nucleolus of Caenorhabditis elegans
por: Lee, Li-Wei, et al.
Publicado: (2012)

Immunometabolism in Caenorhabditis elegans
por: Anderson, Sarah M., et al.
Publicado: (2020)

Immunosenescence in Caenorhabditis elegans
por: Kim, Sieun S., et al.
Publicado: (2022)

Oogenesis in Caenorhabditis elegans
por: Davis, Gregory M., et al.
Publicado: (2023)

The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs
por: Liang, Lung-Yu, et al.
Publicado: (2021)

Oomycete transcriptomics database: A resource for oomycete transcriptomes
por: Tripathy, Sucheta, et al.
Publicado: (2012)

Pseudokinases-remnants of evolution or key allosteric regulators?
por: Zeqiraj, Elton, et al.
Publicado: (2010)

The real role of pseudokinase: linking diabetes to cancers
por: Li, Ke, et al.
Publicado: (2016)

Tribbles Pseudokinase 3 Regulation and Contribution to Cancer
por: Stefanovska, Bojana, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9t425chs8avc1fpdf27fse4aas