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Association between CYP3A4/CYP3A5 genetic polymorphisms and treatment outcomes of atorvastatin worldwide: is there enough research on the Egyptian population?

INTRODUCTION: Atorvastatin is regarded as the most frequently prescribed statin worldwide for dyslipidemia. However, clinical response and risk of adverse effects to statin therapy are associated with genetic variations. Numerous research linked statins pharmacokinetics (PK) variations to genetic po...

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Detalles Bibliográficos
Autores principales: Maslub, Mohammed G., Radwan, Mahasen A., Daud, Nur Aizati Athirah, Sha’aban, Abubakar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523700/
https://www.ncbi.nlm.nih.gov/pubmed/37759317
http://dx.doi.org/10.1186/s40001-023-01038-1