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HSP90, as a functional target antigen of a mAb 11C9, promotes stemness and tumor progression in hepatocellular carcinoma

BACKGROUND: Identification of promising targeted antigens that exhibited cancer-specific expression is a crucial step in the development of novel antibody-targeted therapies. We here aimed to investigate the anti-tumor activity of a novel monoclonal antibody (mAb) 11C9 and identify the antibody trac...

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Detalles Bibliográficos
Autores principales: Liu, Hui-Qi, Sun, Li-Xin, Yu, Long, Liu, Jun, Sun, Li-Chao, Yang, Zhi-Hua, Shu, Xiong, Ran, Yu-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523703/
https://www.ncbi.nlm.nih.gov/pubmed/37759328
http://dx.doi.org/10.1186/s13287-023-03453-x