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The gut metabolite 3-hydroxyphenylacetic acid rejuvenates spermatogenic dysfunction in aged mice through GPX4-mediated ferroptosis

BACKGROUND: Aging-related fertility decline is a prevalent concern globally. Male reproductive system aging is mainly characterized by a decrease in sperm quality and fertility. While it is known that intestinal physiology changes with age and that microbiota is shaped by physiology, the underlying...

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Detalles Bibliográficos
Autores principales:	Jin, Zirun, Yang, Yuzhuo, Cao, Yalei, Wen, Qi, Xi, Yu, Cheng, Jianxing, Zhao, Qiancheng, Weng, Jiaming, Hong, Kai, Jiang, Hui, Hang, Jing, Zhang, Zhe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523725/ https://www.ncbi.nlm.nih.gov/pubmed/37752615 http://dx.doi.org/10.1186/s40168-023-01659-y

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