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Immunosuppressive effects of circulating bile acids in human endotoxemia and septic shock: patients with liver failure are at risk

BACKGROUND: Sepsis-induced immunosuppression is a frequent cause of opportunistic infections and death in critically ill patients. A better understanding of the underlying mechanisms is needed to develop targeted therapies. Circulating bile acids with immunosuppressive effects were recently identifi...

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Detalles Bibliográficos
Autores principales: Leonhardt, Julia, Dorresteijn, Mirrin J., Neugebauer, Sophie, Mihaylov, Diana, Kunze, Julia, Rubio, Ignacio, Hohberger, Frank-Stephan, Leonhardt, Silke, Kiehntopf, Michael, Stahl, Klaus, Bode, Christian, David, Sascha, Wagener, Frank A. D. T. G., Pickkers, Peter, Bauer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523742/
https://www.ncbi.nlm.nih.gov/pubmed/37759239
http://dx.doi.org/10.1186/s13054-023-04620-5