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Long-term PM2.5 exposure disrupts corneal epithelial homeostasis by impairing limbal stem/progenitor cells in humans and rat models

BACKGROUND: Limbal stem/progenitor cells (LSPCs) play a crucial role in maintaining corneal health by regulating epithelial homeostasis. Although PM2.5 is associated with the occurrence of several corneal diseases, its effects on LSPCs are not clearly understood. METHODS: In this study, we explored...

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Detalles Bibliográficos
Autores principales: Hao, Shengjie, Chen, Zhijian, Gu, Yuzhou, Chen, Lu, Sheng, Feiyin, Xu, Yili, Wu, Di, Han, Yu, Lu, Bing, Chen, Shuying, Zhao, Wei, Yin, Houfa, Wang, Xiaofeng, Riazuddin, S. Amer, Lou, Xiaoming, Fu, Qiuli, Yao, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523760/
https://www.ncbi.nlm.nih.gov/pubmed/37759270
http://dx.doi.org/10.1186/s12989-023-00540-y