UBE2S promotes malignant properties via VHL/HIF‐1α and VHL/JAK2/STAT3 signaling pathways and decreases sensitivity to sorafenib in hepatocellular carcinoma

BACKGROUND: Ubiquitin‐conjugating enzyme E2S (UBE2S), an E2 enzyme, is associated with the development of various tumors and exerts oncogenic activities. UBE2S is overexpressed in tumors, including hepatocellular carcinoma (HCC). However, the key molecular mechanisms of UBE2S in HCC still need addit...

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Detalles Bibliográficos
Autores principales: Wu, Junyi, Xu, Xiangjie, Wu, Shasha, Shi, Weiwei, Zhang, Guang, Cao, Yin, Wang, Zhongxia, Wu, Junhua, Jiang, Chunping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523983/
https://www.ncbi.nlm.nih.gov/pubmed/37563971
http://dx.doi.org/10.1002/cam4.6431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523983/
https://www.ncbi.nlm.nih.gov/pubmed/37563971
http://dx.doi.org/10.1002/cam4.6431

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