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Cancer‐associated fibroblasts nurture LGR5 marked liver tumor‐initiating cells and promote their tumor formation, growth, and metastasis

BACKGROUND & AIMS: In liver cancer, leucine‐rich repeat‐containing G‐protein coupled receptor 5 (LGR5) compartment represents an important tumor‐initiating cell (TIC) population and served as a potential therapeutic target. Cancer‐associated fibroblasts (CAFs) is a critical part of the tumor mic...

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Detalles Bibliográficos
Autores principales: Zhang, Mingna, Fang, Yiqiao, Fu, Xia, Liu, Jiaye, Liu, Yang, Zhu, Zhounan, Ni, Yinyun, Yao, Menglin, Pan, Qiuwei, Cao, Wanlu, Li, Zhihui, Dong, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10524013/
https://www.ncbi.nlm.nih.gov/pubmed/37578396
http://dx.doi.org/10.1002/cam4.6408