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Prevalence and spectrum of cancer predisposition germline mutations in young patients with the common late‐onset cancers

BACKGROUND: Pathogenic germline variants (PGVs) can play a vital role in the oncogenesis process in carriers. Previous studies have recognized that PGVs contribute to early onset of tumorigenesis in certain cancer types, for example, colorectal cancer and breast cancer. However, the reported prevale...

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Detalles Bibliográficos
Autores principales: Hao, Shaoyu, Zhao, Ximeng, Fan, Yue, Liu, Zhengchuang, Zhang, Xiang, Li, Wei, Yuan, Hongling, Zhang, Jie, Zhang, Yanxiang, Ma, Tonghui, Tao, Houquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10524041/
https://www.ncbi.nlm.nih.gov/pubmed/37610374
http://dx.doi.org/10.1002/cam4.6445