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A physiologically based pharmacokinetic model for V937 oncolytic virus in mice

Introduction: Oncolytic viruses (OVs) represent a novel therapeutic strategy in oncology due to their capability to selectively infect and replicate in cancer cells, triggering a direct and/or immune-induced tumor lysis. However, the mechanisms governing OV pharmacokinetics are still poorly understo...

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Detalles Bibliográficos
Autores principales: Peribañez-Dominguez, Sara, Parra-Guillen, Zinnia P., Freshwater, Tomoko, Troconiz, Iñaki F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10524596/
https://www.ncbi.nlm.nih.gov/pubmed/37771727
http://dx.doi.org/10.3389/fphar.2023.1211452