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A physiologically based pharmacokinetic model for V937 oncolytic virus in mice
Introduction: Oncolytic viruses (OVs) represent a novel therapeutic strategy in oncology due to their capability to selectively infect and replicate in cancer cells, triggering a direct and/or immune-induced tumor lysis. However, the mechanisms governing OV pharmacokinetics are still poorly understo...
Autores principales: | Peribañez-Dominguez, Sara, Parra-Guillen, Zinnia P., Freshwater, Tomoko, Troconiz, Iñaki F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10524596/ https://www.ncbi.nlm.nih.gov/pubmed/37771727 http://dx.doi.org/10.3389/fphar.2023.1211452 |
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