Sensory deficit screen identifies nsf mutation that differentially affects SNARE recycling and quality control

The AAA(+) NSF complex is responsible for SNARE complex disassembly both before and after membrane fusion. Loss of NSF function results in pronounced developmental and degenerative defects. In a genetic screen for sensory deficits in zebrafish, we identified a mutation in nsf, I209N, that impairs he...

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Detalles Bibliográficos
Autores principales: Gao, Yan, Khan, Yousuf A., Mo, Weike, White, K. Ian, Perkins, Matthew, Pfuetzner, Richard A., Trapani, Josef G., Brunger, Axel T., Nicolson, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10524599/
https://www.ncbi.nlm.nih.gov/pubmed/37027300
http://dx.doi.org/10.1016/j.celrep.2023.112345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10524599/
https://www.ncbi.nlm.nih.gov/pubmed/37027300
http://dx.doi.org/10.1016/j.celrep.2023.112345

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