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Exploring the inhibitory potential of the antiarrhythmic drug amiodarone against Clostridioides difficile toxins TcdA and TcdB

The intestinal pathogen Clostridioides difficile is the leading cause of antibiotic-associated diarrhea and pseudomembranous colitis in humans. The symptoms of C. difficile-associated diseases (CDADs) are directly associated with the pathogen’s toxins TcdA and TcdB, which enter host cells and inacti...

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Detalles Bibliográficos
Autores principales: Schumacher, Judith, Nienhaus, Astrid, Heber, Sebastian, Matylitsky, Jauheni, Chaves-Olarte, Esteban, Rodríguez, César, Barth, Holger, Papatheodorou, Panagiotis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10524773/
https://www.ncbi.nlm.nih.gov/pubmed/37749884
http://dx.doi.org/10.1080/19490976.2023.2256695