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Intestinal epithelial pH-sensing receptor GPR65 maintains mucosal homeostasis via regulating antimicrobial defense and restrains gut inflammation in inflammatory bowel disease

Intestinal epithelial cell (IEC) regulation of barrier function and mucosal homeostasis enables the establishment of a harmonious gut microenvironment. However, host-derived regulatory networks that modulate intestinal antimicrobial defenses have not been fully defined. Herein we generated mice with...

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Detalles Bibliográficos
Autores principales: Li, Gengfeng, Lin, Jian, Gao, Xiang, Su, Huiling, Lin, Ritian, Gao, Han, Feng, Zhongsheng, Wu, Huili, Feng, Baisui, Zuo, Keqiang, Li, Yingchuan, Wu, Wei, Fang, Leilei, Liu, Zhanju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10524779/
https://www.ncbi.nlm.nih.gov/pubmed/37749885
http://dx.doi.org/10.1080/19490976.2023.2257269