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Knockdown of LMNA inhibits Akt/β-catenin-mediated cell invasion and migration in clear cell renal cell carcinoma cells

The LMNA gene encoding lamin A/C is amplified in some clear cell renal cell carcinoma (ccRCC) samples. Our data showed that depletion of the tumor suppressor PBRM1 can upregulate lamin A/C levels, and lamin A/C could interact with PBRM1. However, the role of lamin A/C in ccRCC is not yet fully under...

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Detalles Bibliográficos
Autores principales: Xin, Hui, Tang, Yu, Jin, Yan-Hong, Li, Hu-Li, Tian, Yu, Yu, Cong, Zhao, Ze-Ju, Wu, Ming-Song, Pan, You-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10524799/
https://www.ncbi.nlm.nih.gov/pubmed/37749865
http://dx.doi.org/10.1080/19336918.2023.2260644