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CpxR promotes the carbapenem antibiotic resistance of Klebsiella pneumoniae by directly regulating the expression and the dissemination of bla(KPC) on the IncFII conjugative plasmid

Klebsiella pneumoniae is an important human pathogen known for its resistance to carbapenem antibiotics, especially the increasing carbapenem-resistant hypervirulent variants. The carbapenem resistance is mainly caused by the carbapenemase gene bla(KPC) which was commonly found on the IncFII transfe...

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Detalles Bibliográficos
Autores principales: Liu, Zhiyuan, Guan, Jiahao, Chen, Zhaoyan, Tai, Cui, Deng, Zixin, Chao, Yanjie, Ou, Hong-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10524804/
https://www.ncbi.nlm.nih.gov/pubmed/37672539
http://dx.doi.org/10.1080/22221751.2023.2256427